Materials on this site are intended for medical practitioners. There will be images of some severe wound within this site.
Product Information

    

NOTES

 

  1. Prior to the liquid bandage application on continuously non-healing wounds, thorough cleaning of a wound surface is required with maximum removal of devitalized tissues. The skin around a wound should be treated with the alcohol solution of chlorhexidine or any other antiseptic and then the skin should be dried. Hyperkeratotic growth should be removed with the help of a scalpel. Wound surface as well as callous sides should be moistened with normal saline solution prior to the bandage application.

  2. LOKUS Liquid Bandage should not be applied on wounds with plethorically pyorrhea and with symptoms of pseudomonas and anaerobic infection before its treatment.

  3. In the case of liquid bandage application on septic wounds, daily medical monitoring is required. If the bandage comes off from a wound surface and there is a wound secretion flowing from it, the bandage should be replaced. The LOKUS Liquid Bandage will peel itself once the bandage has absorbed the maximum liquid holding capacity. In case the bandage needs to be removed, it should be done by slow separation from the edge of the healthy skin from any side. The bandage will separate from the wound with minimum discomfort. Cleaning of a wound should be carried out periodically by treating it with antiseptic or ointment of a water-soluble base and then reapply LOKUS Liquid Bandage. If the bandage does not come off from the wound and there is no wound secretion and no dermahemia around, the bandage will stay on a wound surface up to 5 days until self-separation.

  4. In the case of trophic ulcers that has developed against chronic venous insufficiency, in order to lessen possible pain reaction, especially at first bandage application, the ulcer surface should be treated with 10% lidocaine solution.

  5. LOKUS Liquid Bandage can be recommended for patients with singes of II and IIIA type, continuously non-healing wounds and trophic ulcers of any etiology, bedsores, donor wounds, for prophylaxis of inflammatory complications of soft tissues around wires for skeletal extension, skin protection around fistula of gastrointestinal tract, fixing of drainages and catheters.

(according to dissertation materials for inaugural dissertation of M.D. A.A.Kuranov, 2005)

 


SAFETY DATA FOR POLYOL COMPONENT PART A (IN CASE OF ACCIDENTAL CONTACT (BEFORE MIXING)

 

  1. This product is not hazardous as per the Globally Harmonized System of Classification and Labelling (GHS).

  2. Composition: Glycerol, propylene oxide, ethylene oxide polymer.

  3. First Aid Measures:

    • Inhalation: Move person to fresh air; if effects occur, consult a physician.

    • Skin Contact: Wash off with plenty of water.

    • Eye Contact: Flush eyes thoroughly with water for several minutes. Remove contact lenses after the initial 1 – 2 minutes and continue flushing for several additional minutes. If effects occur, consult a physician, preferably an ophthalmologist.

    • Ingestion: If swallowed, seek medical attention. Do not induce vomiting unless directed to do so by medical personnel.

    • Notes to Physician: if burn is present, treat as any thermal burn, after decontamination. No specific antidote. Treatment of exposure should be directed at the control of symptoms and the clinical condition of the patient.

  4. Toxicological Information:

    • Oral Toxicity: Low toxicity if swallowed. Small amounts swallowed incidentally as a result of normal handling operations are not likely to cause injury; however, swallowing larger amounts may cause injury.

    • Dermal Toxicity: Prolonged skin contact is unlikely to result in absorption of harmful amounts.

    • Inhalation Toxicity: at room temperature, exposure to vapor is minimal due to low volatility; single exposure is not likely to be hazardous. Vapor from heated material or mist may cause respiratory irritation. For narcotic effects: No relevant data found.

    • Skin Corrosion/Irritation: Prolonged exposure not likely to cause significant skin irritation. May cause more severe response if skin is abraded (scratched or cut). Material may be handled at elevated temperatures; contact with heated material may cause thermal burns.

    • Eye irritation: May cause slight temporary eye irritation. May cause slight temporary corneal injury.

    • Sensitization: For this family of materials, sensitization studies done in guinea pigs have been negative.

    • For respiratory Sensitization: No relevant data found.

 

 

SAFETY DATA FOR MDI PREPOLYMER BASED COMPONENT PART B (IN CASE OF ACCIDENTAL CONTACT (BEFORE MIXING)

 

  1. Composition: Diphenylmethanediisocyanate

  2. First Aid Measures:

    • If inhaled: Call a physician or poison control center immediately. If unconscious, place in recovery position and seek medical advice.

    • In case of skin contact: If on skin, rinse well with water.

    • In case of eye contact: Flush eyes with water as a precaution. Remove contact lenses. Protect unharmed eye. Keep eye wide open while rinsing. If eye irritation persists, consult a specialist.

    • If swallowed: Keep the respiratory tract clear. Do not give milk or alcoholic beverages. Never give anything by mouth to an unconscious person. If symptoms persist, call a physician.

    • Most important symptoms and effects, both acute and delayed: None known.

  3. Toxicological information:
    Information on likely routes of exposure: None known

 


COMPOSITION AND BASIC PROPERTIES

 

  • The sachet contains one bag of polyol component (15 ml) and another bag of MDI Prepolymer Based component (5 ml).
  • After vigorous mixing, a foamed mass will be formed which cools down upon application on a wound and forms an elastic cover with an area about 10 cm2 with thickness 0.8-1.0 cm.
  • The bandage is non-toxic, and self-aseptic (non – medicated) in the process of preparation and adheres well to healthy skin.
  • The bandage’s thick, elastic and spongy consistency provides wound protection against secondary traumatization and infection.
  • LOKUS Liquid Bandage has the antimicrobic and moderate pain-relieving effect (non – medicated) and also provides long-term absorption of any wound secretion.
  • It has a fine air permeability and moisture-proof properties, making gas composition on a wound optimal for healing.
  • LOKUS Liquid Bandage does not stick to a humid wound surface, allowing painless bandaging without damage to epithelium and granulation upon its removal.

 

 

APPLY TO

 

  • Continuously non-healing and granulating wounds

  • Trophic ulcers

  • Bedsores

  • Donor and degloving injuries

  • To protect skin and as a prophylaxis of osteomyelitis on sites of wires introduction for skeletal extension

  • To protect skin at fistulas of the gastrointestinal tract

  • To strengthen drainage on body skin and etc.

 

 

Relative Contraindications

(Pre-treat before applying Lokus bandage)

 

  • Suppurative Inflammations; remove exudates & treat inflammations.
  • Arterial & Venous bleeding; apply pressure or use a topical hemostatic agent to stop bleeding.
  • Pseudomonas Aeruginosa Infections; perform drainage, debridement and treat with topical antibiotics if applicable.
  • Necrotic Wounds; perform debridement and treat with an antimicrobial agent if applicable.
  • Sensitivity/intolerance to Lokus bandage; consult the doctor first.

 

 

SIDE EFFECTS

 

  • Short term painful sensations may occur on burn wounds. Pre-treats with a local anaesthetic to ease the pain.

 

 

SPECIAL INDICATIONS

 

  • LOKUS Liquid Bandage cannot be applied on the face in the area of nose, lips, eyes.

  • It is recommended to remove hair around a wound prior to applying LOKUS Liquid Bandage.

  • Do not fix used LOKUS Liquid bandage to a wound with adhesive plaster, bandage, etc.

 

 

SAFETY MEASURES

 

  • Do not touch LOKUS Liquid Bandage applied on a wound until it cools down (4 – 6 minutes)

  • In case some LOKUS components fall on skin surface, swab out the fall off surface with ethyl alcohol and wash thoroughly with warm water and soap.

 

 

METHOD OF APPLICATION

 

  • For external use ONLY

 

 

PHARMACEUTICAL FORM

 

  • Double sachet bag of laminated aluminium film

 

 

SHELF LIFE

 

  • 24 months from the date of manufacture

 

 

STORAGE CONDITIONS

 

  • Store in a cold and dry place between 16 – 25 °C.

  • If sachet content is frozen, put the sachet in warm/hot water to defrost before use.

 

 

GENERAL NOTES

 

  • The bandage will harden in around 4 – 6 minutes and it does not need additional fixation on the wound in most cases.

  • The bandage will stay on the wound up to 5 days depending on the amount of wound exudates absorbed into Lokus bandage.

  • The bandage will peel off itself once bandage fully absorbed the exudates. Use warm water if necessary to remove easily and painlessly and for any remaining bandage.